Biojournal of Science and Technology

A Scholarly Journal for Biological Publications

Biojournal of Science and Technology
Volume 4, P-ISSN:2412-5377, E-ISSN:2410-9754, Article ID:m170011

Research Article

Effects of vitamin D and Ca on the occurrence of myocardial infarction in Bangladesh

Jyosna Khanam1, Roksana Yeasmin2, Md. Siddik Alom3 and Md. Bayejid Hosen3,4*

1Institute of Nutrition and Food Science, University of Dhaka, Bangladesh

2Department of Biochemistry, Ibrahim Medical College, Dhaka, Bangladesh.

3Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh

4National Forensic DNA Profiling Laboratory, Dhaka Medical College, Dhaka, Bangladesh

Date of Acceptance: Monday, November 27, 2017
Date of Published: Saturday, December 23, 2017

Address corresponds to

Md. Bayejid Hosen
Scientific Officer
Divisional Forensic DNA Screening Laboratory
Khulna Medical College Hospital
Khulna, Bangladesh
Mobile: 8801723654492

Acedemic Editor: Editor-in-Chief

To cite this article
Jyosna Khanam, Roksana Yeasmin, Md. Siddik Alom and Md. Bayejid Hosen .Effects of vitamin D and Ca on the occurrence of myocardial infarction in Bangladesh.Biojournal of Science and Technology.Volume 4,2017

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Myocardial infarction (MI), which is the most important manifestation of coronary artery disease, is the leading cause of morbidity and mortality in the world. The aim of the present study was to find out the association of vitamin D and calcium (Ca) with the risk of myocardial infarction in Bangladeshi population. A case-control study on 100 cardiac patients who has experienced MI one or more times and 150 control subjects was conducted. The serum troponin I and Ca levels were measured using Demension Xpand Plus Biochemistry Analyser. Vitamin D was estimated by HPLC method. Over all, we found significantly (p< 0.001) higher level of troponin I in cardiac patients when compared to the control subjects. The serum AST and ALP levels were significantly (p< 0.001, respectively) higher in patients when compared to controls. The level of vitamin D and Ca were also significantly lower (p< 0.001, respectively) in patients. There were significantly negative correlations between Troponin I and Vitamin D as well as Ca (r=-0.68, p< 0.001 and r=-0.27, p< 0.05, respectively) levels were found while between Vitamin D and Ca correlated (r=0.43, p< 0.01) positively. Thus our recent study suggested that may have Vitamin D & C and Ca a significant association with the occurrence of myocardial infarction.